MGI Patented DNBSEQ™ Technology – Enhancing Accuracy

DNBSEQ™ provides the advantages of low amplification error rate from DNBs and high-density Patterned Arrays to significantly improve the accuracy of sequencing with a low repetition rate.
Combined with the PCR-free library preparation approach, it reduces the error of entry during amplification and greatly improves the accuracy of detecting SNPs and indels.

Inheriting the advantages of DNBSEQ™ technology, HotMPS achieving fundamental breakthroughs in the nucleotides and enzymes used in the sequencing process to provide stronger signal, less systematic sequence-based errors and compatibility with commonly used library preparation methods.

MGI sequencing platforms
DNBSEQ-G400* is a versatile benchtop sequencer, built with a new Flow Cell system and optimized optical and biochemical systems that support a variety of different sequencing modes and rapid complete sequencing process, providing users with a more streamlined sequencing experience.

DNBSEQ-G400* supports five read lengths, from fertility testing and rapid pathogen detection, to tumor detection, transcriptome, WGBS, WES and WGS comprehensively cover the application needs of scientific research and clinical fields.

DNBSEQ-T7* can output 1~4TB of high-quality data per day. Powered by MGI's unique DNBSEQ™ Technology, DNBSEQ-T7* is using fully upgraded biochemical, fluidics, and optical systems to make sequencing more efficient and productive.

Widely applicable to whole Genome Sequencing, Deep Exome Sequencing, Epigenome Sequencing, Transcriptome Sequencing, Tumor Panel and other large sequencing projects.
Increasing the quality while lowering the cost of high-throughput sequencing

Benchtop Genetic Sequencer DNBSEQ-G99

  • DNBSEQ-G99 is developed based on MGI’s core DNBSEQ™ sequencing technology, Enabled by innovations in biochemistry, optics, fluidics, temperature control, and other core systems, DNBSEQ-G99 boasts the fastest speed amongst all medium-to-low throughput sequencers globally.
  • DNBSEQ-G99 is especially applicable for targeted oncology panel sequencing, infectious disease sequencing, oncology methylation sequencing, small whole-genome sequencing, low-depth whole genome sequencing, individual identification, small panel sequencing of 24-28 samples, or whole-exome sequencing of 1-4 samples.
Rapid sequencing
  • Only 12 hrs for PE150 (from loading to FASTQ).

Flexible throughput
  • Independent loading and running of dual flow cells.

Bioinformatics integrated
  • Option to include built-in bioinformatics module to support sequencing and advanced analysis in a single machine.

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HotMPS is another MGI revolution in sequencing chemistry. The foundation of HotMPS is built on MGI’s proprietary DNBSEQ™ technology together with combinatorial Probe Anchor Synthesis (cPAS) technology. HotMPS inherits the advantages of DNBSEQ™ technology providing low error rates, low duplication rates, and low index hopping, while making fundamental innovations to the nucleotides and enzyme used in the sequencing process.

*This sequencer is only available in selected countries, and its software has been specially configured to be used in conjunction with MGI’s HotMPS sequencing reagents exclusively.
**This sequencing reagent is only available in selected countries.

About MGI
MGI is a leading producer of clinical high-throughput gene sequencers and automation platforms with a vision to lead life science through Intelligent innovation.
MGI’s Patented DNBSEQ™ Technology delivers quality, affordability and performance with:

  • Low error rates
  • Low duplication rates
  • Low index hopping
Aligned with MGI's mission to develop and promote advanced life science tools for future healthcare across Europe and Africa, MGI has launched Customer Experience Centers to enable customers and partners to build new scientific workflows and to amplify knowledge while further developing relevant capabilities and expertise.
© MGI Tech Co., Ltd., 2023, All rights reserved
MGI Tech Co., Ltd. (referred to as MGI) is committed to building core tools and technology to lead life science through intelligent innovation. With a focus on R&D, production and sales of DNA sequencing instruments, reagents, and related products, MGI provides real-time, panoramic, and full-life-cycle equipment and systems for precision medicine, precision agriculture, precision healthcare and other relevant industries. MGI is a leading producer of clinical high-throughput gene sequencers, and its multi-omics platforms include genetic sequencing, medical imaging, and laboratory automation.
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